Prof. Martin Clynes
Dublin City University
Funded Investigators: Prof. Donal O’Gorman, Dublin City University, Prof. Kevin Kavanagh, Maynooth University, Dr. Finbarr O’Sullivan, Dublin City University.
The rationale around building the Molecules III leadership team was our opinion that many of the pure chemistry aspects of SSPC would be enhanced, particularly in terms of attractiveness of us to industry, by having access to systems to evaluate interaction with living biological systems. In particular, we provide a range of in vitro cell culture systems for assessing tissue-specific toxicity and efficacy of specific/drugs in diseases such as cancer and diabetes , biocompatibility and interaction with surfaces. Cell culture systems are generally faster, more ethically acceptable, cheaper and more flexible than animal testing even though some of this may be necessary afterwards - the initial use of cell culture systems is likely to reduce the extent to which animal testing is needed, and the number of animals used.