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Funded Investigators:

Prof. Alan Dobson, University College Cork, Prof. Fergal O’Gara, University College Cork, Dr Marina Rubini, University College Dublin, Prof. Edmond Magner, University of Limerick, Prof. Stephen Connon, Trinity College Dublin, Dr Eoghan McGarrigle, University College Dublin, Dr Gerard McGlacken, University College Cork, Dr Paul Evans, University College Dublin, Prof. Declan Gilheany, University College Dublin, Dr Andrew Phillips, University College Dublin, Prof. Paul Murphy, NUI Galway, Dr Peter Byrne, University College Dublin, Dr Stuart Collins, University College Cork, Prof. Eoin Scanlan, Trinity College Dublin, Dr Joanna McGouran, Trinity College Dublin, Dr Marcus Baumann, University College Dublin.

Theme Leaders:
Prof. Anita Maguire
University College Cork

Molecule I

Prof. Patrick Guiry
University College Dublin

Overall Objective

To develop new methodologies for the asymmetric synthesis of existing APIs and future drug candidates with particular focus on the discovery and application of enzymes, small molecule organocatalysts and organometallic complexes for industrially-relevant, synthetic transformations.

Key Scientific Expertise

Our team consists of internationally recognised researchers with expertise in the following areas of critical interest to the pharmaceutical industry in Ireland:

Industrial Significance


Selecting Route

Selecting the optimal synthetic route for API Manufacture.

Green Pharma

Making pharma greener and continuous manufacturing.

Advanced Procedures

Advanced manufacturing, asymmetrically synthesising complex molecules with more chiral centres.

 Molecules I Research Byte

Check out this 3-minute video from PhD student Robyn Kehoe, University College Cork.

Robyn Kehoe

University College Cork

Listen to a 3-minute presentation of Robyn’s work on Hard Working Palladium Catalysts. Robyn Kehoe works  under the supervision of Dr Ger McGlacken. Robyn talks about One-Pot Reactions are of great interest to the pharmaceutical industry as they reduce waste, reduce labour, cut down on exposure to harmful intermediates, cut down on costs and reduce the amount of time it takes to go from starting material to end product.  And Active Hydrogention of Alkynes.