Research Theme: Manufacturing/Modelling Funded Investigators: Dr Emmet O’Reilly, Dr Luis Padrela Academic Partners: University of Limerick...
De Souza Process – Pregabalin: Transformed Crystallization
The Challenge In 2012, Dr Patrick Frawley started taking Lyrica (Pregabalin) for severe nerve pain associated with his spine. He decided...
CM-NANO: A single process solution to formulate poorly soluble drugs as soluble and directly compressible drug nanoparticles
CM-Nano is a technology to formulate poorly soluble drugs as soluble and directly compressible drug nanoparticles developed by SSPC...
Design, screening and scale-up of cocrystals
The Challenge: Prof. Michael Zaworotko (former SSPC Co-Director and Materials co-theme lead) is leading work on the design, screening and...
Solid-Phase Synthesis of Peptides and Conjugates
Lead Solid Phase Peptide Synthesis (SPPS) is best positioned to meet the need for synthetic peptides, which represent one of the fastest...
Platform Modelling Approach to support Tablet Development, Scale-up and Technology transfer
Project Team The project was devised by Stephen Sheehan, Principal Engineer and Claire O’Reilly, Senior Process Development Engineer at...
Identification of biopharmaceutical drug substances using non-destructive Raman spectroscopy
This project is a Sanofi-UL project led by Prof. Sarah Hudson Challenge: Many biopharmaceutical products have a frozen intermediate step...
Tumour Targeting of an Oxaliplatin / 5FU / Irinotecan based Chemotherapeutic Regimen using Ultrasound Targeted Microbubble Destruction
Platinum-based drugs are used in 50% of anticancer chemotherapeutic regimens. There is a clinical requirement to develop innovative...
The SSPC ‘A Day in Life of a Scientist’ external campaign to highlight the everyday lives of our scientists
The Campaign The ‘A Day in Life of a Scientist’ Campaign employs Point Of View (POV) video to give an insight into the everyday lives of...